Night Bus from Cusco to Arequipa: Prices, Schedules, and Safety in 2025

If you’re planning to travel between Cusco and Arequipa, the night bus is an efficient, safe, and very convenient option. Traveling overnight not only allows you to save a night of accommodation but also to make the most of your time in southern Peru.

In this guide, we cover everything you need to know about traveling overnight between these two cities: schedules, types of service, route safety, and how to reserve your seat with us with full support.

Why Choose a Night Bus Between Cusco and Arequipa?

Most travelers on this route choose the overnight schedule for these reasons:

• You can sleep during the trip and save time

• Arrive early in Arequipa, ready for tours or check-in

• More affordable than flying

• Wide availability of semi-bed and bed buses

• Continue your journey without losing daytime hours

With us, you can select the service that suits you best, from budget options to luxury buses with 180° reclining seats.

Recommended Schedules and Departure Frequency

The Cusco–Arequipa night route operates daily, especially between 6:00 PM and 9:00 PM.
Arrival in Arequipa is usually between 5:00 AM and 7:00 AM, depending on traffic and the type of bus.

By booking with us, we help you choose the best company and schedule according to your itinerary and comfort preferences.

Types of Buses and Available Services

We help you select among different categories based on your needs:

• Economy: basic, functional, with fewer extras

• Semi-bed: wider seats, recline up to 160°, bathroom, air conditioning

• Bed (VIP): recline up to 180°, snacks, blanket, USB charger, personal screen

🔎 Important: During high season (June to September), buses fill up quickly, so early booking is essential.

Route Safety: What You Need to Know

The road between Cusco and Arequipa is fully paved and safe for tourist transportation. All recommended companies comply with:

• Speed controls and GPS monitoring

• Driver changes every few hours

• Safety protocols and up-to-date technical inspections

We only work with reliable and reputable operators, ensuring peace of mind from boarding to arrival.

Reserve Your Night Bus With Us and Travel Worry-Free

When you book your bus with us, you get more than just a ticket:

• Schedule review based on your exact date

• Advice on choosing the right bus

• Fast confirmation and direct WhatsApp support

• Recommendations for transfers and tours in Arequipa if needed

• Safe service without unknown intermediaries

Travel Comfortably and Stress-Free

Whether traveling solo or as a couple, the night bus between Cusco and Arequipa is one of the smartest ways to travel.
You save time, money, and arrive ready to start new adventures.

Overnight travel has never been easier. Check availability with us and secure your seat with full confidence.