Best Bus Companies Between Cusco and Arequipa: Updated Guide 2025

If you’re planning your trip through southern Peru, one of the most common routes connects Cusco and Arequipa, two must-visit cities on any itinerary.
Although several companies operate this route, not all offer the same level of safety, comfort, or passenger service.

In this guide, we show you the best bus companies for this route in 2025, the types of services they provide, and how you can secure your reservation with us—hassle-free and with direct support.

What to Consider When Choosing a Bus Company

Before looking at specific names, it’s important to know which factors make a difference on a long journey like this:

• Safety and fleet maintenance

• Seat comfort (recline, space, type of bus)

• Available schedules and punctuality

• Onboard service, snacks, and entertainment

• Real traveler reviews

• Reliability during high season

We help you book only with trustworthy companies so you can avoid unpleasant surprises or wasted time.

Top Recommended Companies for the Cusco – Arequipa Route

Here are some of the best-rated options by travelers:

Cruz del Sur

• Known for punctuality, safety, and comfortable seats.

• Offers cama (fully reclining) and semi-cama buses with individual screens, air conditioning, and onboard service.

Civa

• Offers both budget and VIP options.

• Great balance between price and comfort, frequently chosen by backpackers with a good budget.

Oltursa

• Modern buses with reliable night services and excellent route support.

• Ideal for travelers who value comfort.

Tepsa

• Solid option with well-organized night trips.

• Cama buses are comfortable for resting during the journey.

Movil Bus

• Stable service with a variety of schedules.

• Useful during high season, though fully reclining seats may not always be available.

Important: Departures and services may vary depending on the season. Booking with us ensures you get the best option according to your date, time, and seat preference.

Why Book With Us Instead of Directly?

You could search on your own, but booking with us guarantees:

• Direct comparison between companies for your exact date and time

• Secure reservation and immediate confirmation

• Assistance before, during, and after your trip

• Combined options with tours, hotels, or transfers

• WhatsApp support to answer any questions

Avoid multiple searches and uncertainty about availability. We take care of everything.

Secure Your Seat Today

With so many options available, the key is choosing wisely and with support. Whether you prefer maximum comfort or a budget-friendly direct trip, we help you find the ideal bus for your Cusco – Arequipa or Arequipa – Cusco route.

Traveling by bus has never been easier or safer. Book with us and enjoy the journey with peace of mind.