How to Travel by Bus from Cusco to Arequipa? 2025 Traveler’s Guide

If you’re planning a route through southern Peru, the bus trip from Cusco to Arequipa is one of the most popular among both domestic and international travelers. Whether you want to save money, enjoy the scenery, or simply travel comfortably, taking the bus is an excellent way to connect these two iconic Peruvian cities.

Here’s everything you need to know to travel safely and comfortably in 2025, and how you can book your seat in advance with us to avoid any issues.

How long is the bus ride from Cusco to Arequipa?

The average travel time on a direct bus between Cusco and Arequipa is 10 to 12 hours, depending on the company, service type, and road conditions.
Most departures are at night, allowing you to save a night of accommodation and arrive in Arequipa in the morning, ready to start your tour or check into your hotel.

Types of bus services: choose how you want to travel

There are several bus categories depending on your budget and comfort preferences:

• Economy Bus: reclining seats up to 140°, no onboard service.

• Semi-Cama Bus: more recline (160°), restroom, air conditioning.

• Cama (VIP) Bus: reclining up to 180°, personal screen, snacks, premium service.

With us, you can choose the service category that best suits your trip and secure your reservation in advance.

Schedules and frequency

Most buses depart from Cusco to Arequipa between 6:00 PM and 9:00 PM, arriving around 5:00 to 7:00 AM the next morning.
Services run daily, but during high season (June–August) it’s recommended to book several days in advance.

Why choose the bus over flying?

Even though flights are available between Cusco and Arequipa, taking the bus is ideal if you:

• Want to travel overnight and save on accommodation

• Prefer to avoid airport procedures and costly transfers

• Wish to enjoy the Andean landscape at a relaxed pace

• Are looking for an economical and safe option

Additionally, booking with us allows you to include terminal transfers, assistance in Arequipa, and recommendations for tours or accommodations.

Book your trip with us and travel stress-free

Booking your bus with us means:

• Personalized advice based on your schedule and budget

• Immediate reservation confirmation

• Direct coordination with reliable bus companies

• Support during your trip via WhatsApp

• Options to combine with tours in Arequipa, Colca Canyon, and more

Plan your Cusco to Arequipa trip today

If you’re ready to travel between two of Peru’s most iconic cities, we are ready to help.
Check updated prices and schedules, choose the best service type, and secure your seat without complications.

Traveling from Cusco to Arequipa has never been easier. Let us handle the details so you can enjoy a safe, smooth, and worry-free journey.